The Terps suffered their fifth loss in the national championship game under coach John Tillman.
The Terps were dominant all game, holding the Blue Devils to a season-low five goals.
DeMaio needed just 39 seconds of overtime to claim a victory for the Terps and set a date with Duke in the semifinals.
Three late goals helped the Terps beat their rivals and clinch their third Big Ten championship.
Bernhardt's career-high eight goals and 10 points helped him become the Terps' all-time leading points scorer.
The Terps trailed in the fourth quarter for the first time all season against the Blue Jays before rallying late to win.
Wierman took over the starting job from senior Justin Shockey, winning nine of 13 faceoffs in the first half.
Jared Bernhardt, Anthony DeMaio, Bubba Fairman and Daniel Maltz accounted for all but two of the Terps' goals.
Jared Bernhardt scored five goals to break Matt Rambo's all-time scoring record.
“Big Ten lacrosse is big guy lacrosse."