The Terps are undefeated since her injury on Dec. 3.
Five players scored in double-digits for the Terps, who continued their undefeated start in Big Ten play.
Owusu and Miller scored 20 points each.
"We're just trying to do different things to make us a championship team."
The sophomore's career day helped the Terps hold off the Nittany Lions.
Mimi Collins scored a career-high 22 points to lead the Terps.
Owusu and Miller combined for 53 points against Towson, including eight three-pointers.
The Terps held the Tigers to 39% shooting.
The Terps are averaging 17.7 turnovers per game.
Katie Benzan tied a school record with eight three-pointers.