Ayala tied a career-high with 23 points, but the Terps failed to make a field goal in the last 7:32 of the game.
The Terps coughed the ball up four times in a three minute stretch in the second half, halting their comeback efforts.
The Terps trailed as much as 18 in the game.
The Terps held the Golden Gophers to just 30.4 percent shooting.
The Alabama transfer has started the last six games for the Terps.
Five Terps scored in double figures, led by Aaron Wiggins' 21 points.
Morsell is out after suffering a facial fracture against No. 16 Michigan on New Year's Eve.
The Terps have six players averaging at least nine points per game.
“He has a different energy about himself, a different confidence."
The sophomore had a career-high 32 points in the victory.