The Terps rallied from two sets down to get themselves to a fifth set against the Wildcats.
Led by Erika Pritchard's 16 kills, the Terps rallied for their fifth win of the season.
The Boilermakers racked up seven service aces while the Terps had none.
After topping Indiana on Friday, the Terps couldn't put it together against the Boilermakers.
Hoosiers outside hitter Breana Edwards racked up 39 kills in the match.
Katie Myers and Nicole Alford are expected to miss the match against Indiana.
Smith didn’t record a kill but notched three blocks.
“You probably don’t understand it until you sit in this seat, but we got out-coached tonight," Hughes said.
The Terps hit a season-low .045 in the match.
Myers was out with a foot injury sustained in practice.