"We saw a lot of fight when we went down," coach Ray Leone said.
The Terps scored in the opening minute of the game, but struggled to keep up with the Midshipmen's attack.
Catherine DeRosa's 74th-minute penalty lifted the Terps to their third straight win.
The Terps already boast four different goal scorers through their first two games and look to tally more as they host Richmond on Thursday.
Locksley opened up scoring in the first half, helping push the Terps to back-to-back wins.
The Terps dominated on the attacking end, getting three goals past the Owls after scoring just eight total in the Spring 2021 season.
The Terps were winless in the spring, but with a majority of players returning, coach Ray Leone's squad wants to show improvement.
"I think a big part of Maryland culture and being a part of the Maryland athletics family is the theme of resilience."
The Buckeyes scored three goals in the second half.
The Terps fell 3-1 in their first matchup with the Buckeyes back on March 4.