After taking the lead in the first set, the Terps dropped three straight to fall to the Illini.
The Terps racked up 14 blocks across the three sets.
Erika Pritchard led the Terps with 14 kills.
Csire and Dowler combined for six straight points to push the Terps past the Hoosiers on Saturday.
Sam Csire and Erika Pritchard combined for 33 kills.
The Terps were without key players Sam Burgio and Jada Gardner.
The Terps are the Big Ten's leader in blocks, with 2.71 per match.
The captain had 18 kills and 16 digs for the Terps in Friday's 3-2 victory over Michigan.
Laila Ricks and Lexy Finnerty starred as the Terps claimed their first victory of the season.
Outside hitter Erika Pritchard notched a team-high 21 kills as the Terps fell just short of a second straight victory over the Wolverines.