The Terps' sweep of the Bears was their first road sweep under coach Rob Vaughn.
The Terps scored four runs in the first inning, followed by a solo home run from Bobby Zmarzlak in the third to take control of the matchup.
Dean pitched seven shutout innings against the Bears in the Terps' 2022 season opener.
The Terps will open their season with a challenge at Baylor.
Matt Orlando's double in the eleventh inning and six straight strikeouts from Ryan Ramsey set the Terps up for a monumental win.
"This is the first time … where I feel like that was a legit complete game."
The Terps saw their six-game winning streak snapped.
Ben Cowles' four-RBI performance lifted the Terps to their fourth straight victory.
Strong performances from Nick Dean and Logan Ott pushed the Terps to victories over Iowa and Northwestern.