The Terps outscored the Scarlet Knights 10-3 in the second half.
The Terps are giving up 8.67 goals per game, the best average in the Big Ten.
Wisnauskas notched a career-high seven assists against Johns Hopkins.
The Terps scored eight unanswered goals in the third period to put the game away.
"We are playing for the crab trophy, so it's going to be special."
The Terps beat Penn State 13-7 in their first road test of the season.
Jared Bernhardt, Nick Grill and Logan McNaney picked up the honors after a dominant win over Penn State.
The sophomore made a career-high 16 saves against Penn State.
Three players — Daniel Maltz, Jared Bernhardt and Logan Wisnauskas — netted hat tricks Friday evening.
The last time both sides faced each other, the Nittany Lions claimed a 13-10 victory — their first win over the Terps since 1924.