Mikesell scored a career-high 33 points against her former team and went 5-for-5 from three.
“She’s a bucket. You look at her and you know she’s a bucket."
Coach Brenda Frese added Shakira Austin and Blair Watson to the starting five.
Guard Ashley Owusu also earned Big Ten Freshman of the Week honors.
Guard Taylor Mikesell led the way with 23 points.
Before a 21-point surge in the fourth quarter, the Terps' offense has looked off.
The Terps outscored the Dukes 29-11 in the final frame.
Austin scored two points in 14 minutes against South Carolina.
Owusu posted team highs in points and rebounds.
The Terps shot 31.4 percent against the Gamecocks.