Jennifer Brann allowed no runs and one hit while striking out seven in 4.1 innings.
The Terps surrendered four runs in the fifth inning of the second game to fall behind for good.
A bases-clearing error in the seventh inning lifted the Terps to a series win.
The Terps managed just three hits and failed to score against the Nittany Lions.
The Terps took a low-scoring defensive battle in game one and exploded for 11 runs in game two.
The Wolverines battered the Terps' pitching for 12 hits.
The Terps managed just one run in 14 innings of play Saturday.
The Terps' bats fell quiet in game one but roared to life in game two for a mercy-rule victory.
The Terps lost their third straight game by at least eight runs.