The Terps used a second quarter in which they outscored the Hawkeyes 27-8 to take a commanding lead that they never surrendered.
The Terps narrowly avoided an upset to notch their fourth straight win.
The Terps missed all 17 three-pointers but still pulled out a victory.
The Terps outscored the Fighting Illini 31-8 in the third quarter, with 17 of their points coming of Illinois turnovers.
Northwestern missed all 13 of its shots from the field in the second quarter as the Terps held the Wildcats to just two points in the frame.
The Terps blew out the Buckeyes just days after giving up 96 points to Iowa.
The rout was the Terps' largest margin of victory over a top-10 opponent in program history.
Clark scored 42 as the Terps gave up a season-high 96 points to the Hawkeyes.
Caitlin Clark and Monika Czinano combined for 70 points as the Terps dropped their third Big Ten game of the season.
McDaniel tied her season high with 19 minutes against Penn State. She notched eight points, four rebounds and added two steals.