The Terps lost to the Nittany Lions for the first time since 2003 and gave up the second-most points in program history.
The Terps' loss to Michigan knocked them back down to a .500 conference record for the fourth time this season.
The Terps were outscored 48-21 after halftime.
The Terps restored their winning record in Big Ten play behind a 12-2 fourth-quarter run powered by Jakia Brown-Turner.
The Terps lost a two-point halftime and were outscored by 10 in the second half.
Bri McDaniel also set a career high in points for the fifth time this season in the Terps' dismantling of the Boilermakers.
The Terps couldn't shut down a strong Spartans offense for the full 40 minutes as they dropped their second Big Ten game of the season.
The Terps shot 44.4 percent from three and finished with a season-low in turnovers to find their first win of 2024.
The Terps dropped their fourth game of the season as Shyanne Sellers logged just four points and fouled out.