Maryland began the season ranked No. 15.
Charles finished with 25 points and 16 rebounds.
Kaila Charles scored a game-high 22 points.
The Scarlet Knights are seventh in the Big Ten.
In 2017, Maryland went 23-0 en route to its 14th national championship.
Maryland women’s lacrosse enters the season as conference favorites behind its three Big Ten Players to Watch
Attacker Megan Whittle, midfielder Jen Giles and goaltender Megan Taylor were named as Big Ten Players to Watch.
The Terps matched their highest ranking of the campaign.
Charles averaged 24.5 points in two games.
She scored 13 points on Thursday against Northwestern.
The Terps stifled the Wildcats after the first quarter.