He entered the Grand Ballroom on Friday night clad in a black and white striped hoodie and red breakaway pants.

From there, he stripped to more red breakaway pants, then to black pants and a white t-shirt.

It was the introduction to YouTube sensation turned Comedy Central star Bo Burnham’s performance in Student Entertainment Events’ fall comedy show.

“Never waste a moment,” Burnham said, completing a transition to the other side of the stage with large hand gestures and quirky movements, explaining that every moment can be a comic moment.

It was a phrase that turned into his show’s mantra. The 22-year-old hardly left a spot of dead time in segues between segments, combining keyboard, guitar and vocals for a mix between a comedy show and a concert.

All 800 seats of Burnham’s show had sold out soon after they went on sale at midnight Oct. 1. Those seated in the closest rows had waited in line for the 7 p.m. show since as early as 5 p.m.

Burnham started performing satirical songs on YouTube in 2006 and after millions of YouTube views, rose to Comedy Central fame at 18 years old as the youngest person to record the half-hour special “Comedy Central Presents.”

Known for his R-rated humor, Burnham — who did not grant interviews — occasionally touched on deeper issues, such as the superficiality in the world of famous comedians and the meaning of love.

Anthony Schams, a sophomore biochemistry major seated in the front row in the right section, had carried in a Burnham album for him to sign in his sweatshirt pocket.

“His comedy’s just unique,” Schams said. “He uses music to make taboo issues more easy to talk about.”

A few had come from other area universities to see Burnham perform.

“He’s offensive but creative about it,” said Paige Goodwin, a sophomore at Anne Arundel Community College, who was wearing a t-shirt that spelled out Burnham’s song “New Math” with lyrics broken down into math equations.

His jokes were often filled with swear words and sexual references, which were woven into his readings of mock children’s stories and poetry in addition to his original songs.

His set list included:

1. “Deep in Milwaukee” (“Have you ever stopped/ to watch a blue bird drop/ From a tree and take to the air?/ Me neither.”)

2. “Men and Women” (after which he ended abruptly and told the audience not to applaud and to just sit there, because it’s fun)

3. “Love Is”

4. “Repeat Stuff” (which he started by singing a run of “Jason DeRulo,” criticizing mainstream pop music)

5. “Oh Bo”

He used on-the-spot humor as well, with humor interpreters signing with American Sign Language, jokes about Maryland Madness and his allowance of photography and videos at the show – he said that he started the Internet, referencing his rise over YouTube.

Burnham’s show was about an hour long, a surprise to many students who had expected him to run longer.

Senior English and theatre major Sarah Nowak said she and her friends were obsessed with Burnham’s comedy their freshman year, so attending his comedy show made everything come full circle.

“Now it’s senior year and I actually got to see him,” she said.