The Terps prevailed over the Hawkeyes thanks to strong defensive play down the stretch on the road.
The Terps slowed Caitlin Clark on the road in Iowa City, moving to 19-6 on the season.
The Terps forced Wisconsin into 26 turnovers on Wednesday, and outrebounded the Badgers by 12.
The Terps were in a similar position when they played then-No. 5 NC State.
Four Terps clocked double digits, led by Angel Reese with 19 points.
Sellers has exceeded expectations for the Terps in her freshman season.
Chloe Bibby, Katie Benzan, Channise Lewis and Zoe Young were recognized before and during the Terps' game against Nebraska.
The Terps never trailed in a thrashing of the Cornhuskers on senior day.
Ashley Owusu went down with an apparent ankle injury in the second quarter, and freshman Shyanne Sellers served as a strong replacement.
Penn State found a way to work around the Terps' defense with Masonius out of the lineup.